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Zemni I et al. reviewed clinic and pathological characteristics and outcomes of gastric signet ring cell carcinomas (J Gastric Surg 2020; 2(3):71-78) focusing on the major prognostic factors of progression-free survival and overall survival including hypoproteinemia, tumor size, stenosis, advanced stage, and recurrence. The majority of patients were males under 60 years of age. The data were compared with those of non-signet ring cell gastric carcinomas. There was no significant difference in the 5 years overall survival between the compared groups. The increasing incidence of aggressive tumors in an advanced stage with poor outcome is emphasized and additional comments are about gastric signet ring cell tumors that affected a female and an elderly male.


gastric cancer signet ring cell carcinoma pathology prognosis

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How to Cite
Santos, V. M., & Modesto, L. C. (2020). Gastric signet ring cell carcinoma . Journal of Gastric Surgery, 2(4), 139–140.


  1. Zemni I, Mansouri H, Ben Safta I, Ayadi MA, Ben Dhiab T, Chargui R, et al. Resectable gastric signet ring cell carcinoma: clinicopathological characteristics and survival outcomes. Journal of Gastric Surgery. 2020;2:71-8.
  2. dos Santos VM, Rodrigues DB, Castro EC, Saldanha JC, Soares S, Teixeira VP, et al. Widespread hematogenous metastases and Trousseau's syndrome in gastric adenocarcinoma. Rev Hosp Clin Fac Med Sao Paulo. 2001;56:91-6.
  3. Santos VM, Carneiro MV, Soares VVP, Silva SA, Yano VM, Garcia C. An elderly man with gastric cancer, Saint's triad and Heyde's syndrome. Rev Gastroenterol Peru. 2018;38:289-92.

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