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Several meta-analyses have tried to defi ne the role of minimally invasive approaches. However, further evidence to get a wider spread of these methods is necessary. Current studies describe minimally invasive surgery as a possible alternative to open surgery but deserving further clarifi cation. However, despite the increasing interest, the difficulty of planning prospective studies of adequate size accounts for the low level of evidence, which is mostly based on retrospective experiences.
A multi-institutional prospective study allows the collection of an impressive amount of data to investigate various aspects of minimally invasive procedures with the opportunity of developing several subgroup analyses.
A prospective data collection with high methodological quality on minimally invasive and open gastrectomies can clarify the role of diff erent procedures with the aim to develop specifi c guidelines.
Methods and analysis:
a multi-institutional prospective database will be established including information on surgical, clinical and oncological features of patients treated for gastric cancer with robotic, laparoscopic or open approaches and subsequent follow-up.
The study has been shared by the members of the International study group on Minimally Invasive surgery for GASTRIc Cancer (IMIGASTRIC)
The database is designed to be an international electronic submission system and a HIPPA protected real time data repository from high volume gastric cancer centers.
This study is conducted in compliance with ethical principles originating from the Helsinki Declaration, within the guidelines of Good Clinical Practice and relevant
Trial registration number:


Minimally invasive surgery Gastrectomy Gastric surgery Robotic surgery Laparoscopy Prospective study Database

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How to Cite
Desiderio, J., Lin, J.-X., Norero, E., Borghi, F., Marano, A., Cianchi, F., Badii, B., Qi, F., Liu, T., Reim, D., Novotny, A., Coratti, A., Guerra, F., Nguyen, N. T., Alimoglu, O., Ozemir, I. A., Brower, S., Bazzocchi, F., Avanzolini, A., Solaini, L., Ioannidis, O., Chatzakis, C., Loutzidou, L., Isik, A., Cesari, M., Pernazza, G., Azagra, J.-S., Goergen, M., Zhou, Y., Cao, S., Gagnière, J., Pezet, D., D’Imporzano, S., Saint-Marc, O., Sindayigaya, R., Zang, L., Coburn, N. G., Kayaalp, C., Arcuri, G., Giovanardi, F., Trastulli, S., Parisi, A., Zheng, C.-H., & Huang, C.-M. (2019). Prospective, observational, multicenter study on minimally invasive gastrectomy for gastric cancer: robotic, laparoscopic and open surgery compared on operative and follow-up outcomes - IMIGASTRIC II study protocol: IMIGASTRIC II. Journal of Gastric Surgery, 1(1), 9–15.

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